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Pizza Enchiladas with Ground Beef

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These Pizza Enchiladas with Ground Beef are a fun and family-friendly fusion of two comfort food favorites—cheesy pizza and saucy enchiladas. Filled with seasoned beef, pepperoni, gooey mozzarella, and wrapped in soft flour tortillas, this easy weeknight dinner is customizable and ready in just 40 minutes. A crowd-pleasing recipe perfect for pizza night or casual gatherings.

  • Author: Julia
  • Prep Time: 15 minutes
  • Cook Time: 25 minutes
  • Total Time: 40 minutes
  • Yield: 4–6 servings
  • Category: Dinner, Casserole
  • Method: Baking
  • Cuisine: American, Fusion

Ingredients

  • 1 lb lean ground beef
  • 1 medium yellow onion, diced
  • 1 cup pepperoni slices
  • 8 flour tortillas
  • 2 cups shredded mozzarella cheese
  • 1 1/2 cups pizza sauce (or marinara)
  • 1 teaspoon Italian seasoning
  • 1/2 teaspoon garlic powder
  • Salt and pepper, to taste
  • Olive oil, for sautéing

Instructions

  1. Preheat oven to 375°F (190°C).
  2. In a large skillet, heat olive oil over medium heat. Add diced onion and sauté for 3–4 minutes until soft.
  3. Add ground beef and cook until browned, breaking it up with a spoon. Season with salt, pepper, garlic powder, and Italian seasoning.
  4. Stir in half the pepperoni slices and 1/2 cup of pizza sauce. Simmer for a few minutes to blend flavors.
  5. Spoon beef mixture into each flour tortilla. Add a sprinkle of mozzarella, roll up, and place seam-side down in a greased 9×13-inch baking dish.
  6. Pour remaining pizza sauce over enchiladas. Top with remaining cheese and pepperoni.
  7. Bake uncovered for 20–25 minutes, until cheese is melted and bubbly.
  8. Let cool a few minutes before serving.

Notes

  • Add black olives, bell peppers, or red pepper flakes for extra flavor.
  • Works great with whole wheat or low-carb tortillas.
  • Mix in provolone or cheddar with mozzarella for extra cheesiness.
  • Swap pepperoni for sausage or omit for a simpler version.

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