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Cheesy Stuffed Meatloaf

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Cheesy Stuffed Meatloaf is a hearty twist on a classic comfort food, featuring a juicy, seasoned beef loaf with a gooey cheddar cheese center and a sweet-tangy glaze. Perfect for family dinners, meal prep, or even party appetizers, this cheesy meatloaf recipe is as comforting as it is irresistible.

  • Author: Julia
  • Prep Time: 20 minutes
  • Cook Time: 55 minutes
  • Total Time: 1 hour 15 minutes
  • Yield: 6 servings
  • Category: Dinner, Main Course
  • Method: Baked
  • Cuisine: American
  • Diet: Low Lactose

Ingredients

2 lbs ground beef

1 cup breadcrumbs

1 small onion, finely chopped

2 garlic cloves, minced

2 large eggs

½ cup milk

2 tablespoons Worcestershire sauce

1 teaspoon salt

½ teaspoon black pepper

1½ cups cheddar cheese (cut into cubes or shredded)

½ cup ketchup

1 tablespoon mustard

2 tablespoons brown sugar (optional, for sweetness)

Fresh parsley, chopped (for garnish)

Instructions

Preheat oven to 375°F (190°C). Grease a loaf pan or line a baking sheet with parchment paper.

In a large bowl, combine ground beef, breadcrumbs, onion, garlic, eggs, milk, Worcestershire sauce, salt, and pepper. Mix until just combined.

Press half of the meat mixture into the prepared pan.

Layer cheddar cheese in the center, leaving a small border around the edges.

Cover with the remaining meat mixture, pressing to seal the edges tightly.

In a small bowl, whisk together ketchup, mustard, and brown sugar. Spread evenly over the meatloaf.

Bake for 45–55 minutes, or until internal temperature reaches 160°F (71°C) and glaze is caramelized.

Let rest 10 minutes before slicing. Garnish with parsley and serve.

Notes

Swap cheddar for mozzarella, pepper jack, or Monterey Jack for different flavor profiles.

For a lighter version, use ground turkey or chicken.

Shape into mini loaves or muffin tin bites for appetizers.

Freeze cooked or uncooked meatloaf for up to 2 months.

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